Monday, June 02, 2014

Fat men die of prostate cancer

Adipose tissue surrounding the prostate gland of men with obesity, creates favorable conditions for the progression of prostate cancer.

What is the prostate gland
The prostate gland - is musculo-glandular organ located below the bladder and surrounding the initial portion of the urethra. The main function of the prostate is to produce secretions, which is part of semen. Ducts of the prostate glands open into the urethra.

Prostate cancer
In the early stages of prostate cancer does not manifest itself. Complaints are associated with tumor spread and metastasis. At the stage the only manifestation of the lack of symptoms, allowing the disease to suspect, is to increase blood levels of prostate specific antigen (PSA). As prevention of prostate cancer for all men should conduct an annual PSA test beginning at age 45.

By increasing the size of the tumor shows the following symptoms:
  • Frequent urination
  • Difficulty urinating
  • Urinary incontinence
  • urge to urinate.
The essence of the study

Scientists have received samples of adipose tissue surrounding the prostate gland in men with benign prostatic hyperplasia, prostate cancer and prostate cancer. Regardless of prostate disease in men with obesity , there is increased activity of genes in fat cells. These genes encode proteins involved in the immune response, inflammation, growth, reproduction, and cell death.

Increase in the activity of genes leads to inhibition of the immune response and stimulates the formation of new blood vessels, which creates favorable conditions for the progression of prostate cancer. The study's authors hope that the findings will more carefully selected treatments for patients with obesity.


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